Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 8/20 | 0.49 |
| ▸ | TNF | P01375 | 2/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 9/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 5/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26092916 | 1.00 | IL1B (0.49) | IL1BTNFMAPK8NLRP3MAPK9 | |
| SCHEMBL26437243 | 0.91 | IL1B (0.41) | IL1BTNFNLRP3KCNH2 | |
| SCHEMBL27182193 | 0.85 | IL1B (0.52) | IL1BTNFNLRP3KCNH2 | |
| SCHEMBL26092873 | 0.85 | IL1B (0.52) | IL1BTNFNLRP3KCNH2 | |
| SCHEMBL30375405 | 0.85 | IL1B (0.52) | IL1BTNFNLRP3KCNH2 | |
| SCHEMBL30684741 | 0.85 | IL1B (0.52) | IL1BTNFNLRP3KCNH2 | |
| Hydrochloric Acid SCHEMBL29975485 | 0.84 | IL1B (0.52) | IL1BTNFNLRP3KCNH2 | |
| SCHEMBL29326630 | 0.83 | NLRP3 (0.52) | IL1BTNFNLRP3KCNH2 | |
| SCHEMBL26093124 | 0.83 | IL1B (0.60) | IL1BTNFNLRP3KCNH2 | |
| SCHEMBL30374870 | 0.83 | IL1B (0.57) | IL1BNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250002470-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | ZHEJIANG AIXPLORER BIOTECH CO., LTD. (CN) | 2025-01-02 | — | — | US | disclosed |
| EP-4421068-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Zhejiang Aixplorer Biotech Co., Ltd. (CN) | 2024-08-28 | — | — | EP | disclosed |
| CN-116102535-A | Nitrogen-containing compound, preparation method and application thereof | 索智生物科技（浙江）有限公司 | 2023-05-12 | — | — | CN | disclosed |
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250002470-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | NOD1, NLRP3, NLRP1 | IL1B 9/4885TNF 186/4885MAPK8 472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.