Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.47 |
| ▸ | IL1B | P01584 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26437582 | 0.88 | NLRP3 (0.37) | NLRP3IL1BKCNH2IRAK1IRAK4 | |
| SCHEMBL26437566 | 0.84 | IL1B (0.48) | NLRP3IL1BKCNH2 | |
| SCHEMBL26436753 | 0.84 | NLRP3 (0.46) | NLRP3IL1B | |
| SCHEMBL26436300 | 0.84 | NLRP3 (0.53) | NLRP3IRAK1IRAK4 | |
| SCHEMBL26437599 | 0.82 | NLRP3 (0.46) | NLRP3IL1BKCNH2 | |
| SCHEMBL26437416 | 0.81 | IL1B (0.41) | NLRP3IL1B | |
| SCHEMBL26437272 | 0.80 | NLRP3 (0.41) | NLRP3 | |
| SCHEMBL26437600 | 0.79 | NLRP3 (0.57) | NLRP3IL1BKCNH2IRAK1 | |
| SCHEMBL26437588 | 0.78 | NLRP3 (0.76) | NLRP3IL1B | |
| SCHEMBL26437583 | 0.71 | IL1B (0.51) | NLRP3IL1BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |