Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | LATS1 | O95835 | 2/20 | 0.38 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 3/20 | 0.35 |
| ▸ | IL1B | P01584 | 3/20 | 0.35 |
| ▸ | IRAK1 | P51617 | 3/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26437579 | 0.88 | NLRP3 (0.55) | NLRP3KCNH2LATS1LATS2CNR1 | |
| SCHEMBL26436751 | 0.86 | NLRP3 (0.46) | NLRP3KCNH2LATS1LATS2CNR1 | |
| SCHEMBL26437564 | 0.85 | NLRP3 (0.72) | NLRP3KCNH2LATS1LATS2IL1B | |
| SCHEMBL26436298 | 0.85 | NLRP3 (0.51) | NLRP3KCNH2LATS1LATS2CNR1 | |
| SCHEMBL26089652 | 0.82 | IL1B (0.43) | NLRP3KCNH2CNR1SYKHTR1A | |
| SCHEMBL26437415 | 0.82 | IL1B (0.43) | NLRP3KCNH2CNR1SYKHTR1A | |
| SCHEMBL26437270 | 0.81 | NLRP3 (0.42) | NLRP3KCNH2CNR1SYKHTR1A | |
| SCHEMBL26437601 | 0.79 | NLRP3 (0.47) | NLRP3KCNH2IL1BIRAK1 | |
| SCHEMBL26437588 | 0.75 | NLRP3 (0.76) | NLRP3IL1B | |
| SCHEMBL26437599 | 0.75 | NLRP3 (0.46) | NLRP3KCNH2IL1BTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |