SCHEMBL2644098

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL642328	0.90	GCK (0.40)	GCKALDH1A1DAGLASMN1; SMN2POLB
	SCHEMBL643275	0.89	PTGS2 (0.41)	GCKALDH1A1GAAKDM4EHPGD
	SCHEMBL2643958	0.86	ALDH1A1 (0.43)	GCKALDH1A1GAAKDM4EHPGD
	SCHEMBL2644255	0.85	GCK (0.39)	GCKALDH1A1GAAKDM4EHPGD
	SCHEMBL2645030	0.85	GCK (0.47)	GCKALDH1A1GAAKDM4EHPGD
	SCHEMBL2645247	0.84	GCK (0.44)	GCKALDH1A1KDM4ESMN1; SMN2POLB
	SCHEMBL2643952	0.84	GCK (0.39)	GCKALDH1A1GAAKDM4EHPGD
	SCHEMBL644806	0.81	GCK (0.54)	GCKL3MBTL1
	SCHEMBL642785	0.81	ALDH1A1 (0.46)	GCKALDH1A1GAAKDM4EHPGD
	SCHEMBL2644143	0.81	MAOB (0.43)	GCKALDH1A1GAAKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.