SCHEMBL2644271

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL643275	0.88	PTGS2 (0.41)	HAO1GCKPTGS1PTGS2DAGLA
	SCHEMBL643866	0.82	TTR (0.38)	GCKTTRPTGS1PTGS2LMNA
	SCHEMBL2644488	0.82	PTGS2 (0.39)	GCKPTGS1PTGS2LMNA
	SCHEMBL2644950	0.82	GCK (0.40)	HAO1GCKKDM4EALDH1A1GLA
	SCHEMBL2645261	0.82	GCK (0.49)	GCKPTGS1PTGS2KDM4EALDH1A1
	SCHEMBL644145	0.81	GCK (0.64)	GCK
	SCHEMBL2644098	0.80	GCK (0.40)	GCKDAGLAABHD6KDM4EALDH1A1
	SCHEMBL2643958	0.79	ALDH1A1 (0.43)	GCKDAGLAABHD6KDM4EALDH1A1
	SCHEMBL2645307	0.79	GCK (0.52)	GCKALDH1A1GAAHPGD
	SCHEMBL643684	0.79	GCK (0.40)	GCKPTGS1PTGS2DAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.