⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18427480 | 0.78 | — | — | |
| SCHEMBL19346305 | 0.78 | HTR4 (0.30) | — | |
| SCHEMBL20759052 | 0.77 | — | — | |
| SCHEMBL25125341 | 0.76 | HTR4 (0.32) | — | |
| SCHEMBL14210392 | 0.76 | HTR4 (0.32) | — | |
| SCHEMBL24437696 | 0.76 | LMNA (0.31) | — | |
| SCHEMBL10121124 | 0.75 | OPRK1 (0.30) | — | |
| SCHEMBL20055052 | 0.74 | — | — | |
| SCHEMBL18873126 | 0.74 | PIK3CD (0.47) | — | |
| SCHEMBL22565081 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230135894-A1 | MK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-05-04 | — | — | US | disclosed |