SCHEMBL2644535

SCHEMBL2644535

[CH]=CCCOC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6336160 0.81
SCHEMBL7524031 0.79
SCHEMBL3021594 0.77
SCHEMBL3033812 0.77 ALDH1A1 (0.39)
SCHEMBL10904780 0.77 ALDH1A1 (0.39)
SCHEMBL10887342 0.77 ALDH1A1 (0.39)
SCHEMBL11319609 0.72 LPAR3 (0.30)
SCHEMBL7773058 0.72 LPAR3 (0.30)
SCHEMBL310640 0.72
SCHEMBL778646 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7598244-B2 [1,2,4]triazolo[1,5,a]pyrimidin-2-ylurea derivative and use thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-10-06 US claimed
US-12030868-B2 Prodrugs of CGRP antagonists PFIZER IRELAND PHARMACEUTICALS (IE) 2024-07-09 US disclosed
US-20240067651-A1 PRODRUGS OF MYELOPEROXIDASE INHIBITORS BIOHAVEN THERAPEUTICS LTD. 2024-02-29 US disclosed
EP-4289810-A1 METHOD FOR PRODUCING (2-METHOXYETHYL) VINYL ETHER, AND METHOD FOR REFINING (2-METHOXYETHYL) VINYL ETHER Maruzen Petrochemical Co., Ltd. (JP) 2023-12-13 EP disclosed
CN-114945573-A Prodrugs of myeloperoxidase inhibitors 拜奥海芬治疗学有限公司 2022-08-26 CN disclosed
US-20210395223-A1 PRODRUGS OF CGRP ANTAGONISTS PFIZER IRELAND PHARMACEUTICALS (IE) 2021-12-23 US disclosed
EP-3863629-A1 PRODRUGS OF CGRP ANTAGONISTS Biohaven Pharmaceutical Holding Company Ltd. (US) 2021-08-18 EP disclosed
CN-112888438-A Prodrugs of CGRP antagonists 拜尔哈文制药股份有限公司 2021-06-01 CN disclosed
WO-2021072140-A1 PRODRUGS OF MYELOPEROXIDASE INHIBITORS BIOHAVEN THERAPEUTICS LTD. (US) 2021-04-15 WO disclosed
EP-3514133-B1 METHOD FOR REMOVING OR COLLECTING 2-ALKOXYETHANOL, AND METHOD FOR PRODUCING (2-ALKOXYETHYL) VINYL ETHER MARUZEN PETROCHEM CO LTD (JP) 2020-11-25 EP disclosed
EP-0872484-A1 ORGANOSILICON COMPOUNDS, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 1998-10-21 EP disclosed
EP-0559860-B1 HALOVINYL-DERIVATIVES HOFFMANN LA ROCHE (CH) 1996-02-14 EP disclosed
US-5364556-A Halovinyl-derivatives HOFFMANN-LA ROCHE INC. (US) 1994-11-15 US disclosed
EP-0430001-B1 Process for preparing benzaldehydes BAYER AG (DE) 1993-12-22 EP disclosed
WO-1993007234-A1 HALOVINYL-DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 1993-04-15 WO disclosed
US-5082976-A PROCESS FOR THE PREPARATION OF BENZALDEHYDES BAYER AKTIENGESELLSCHAFT (DE) 1992-01-21 US disclosed
EP-0430001-A1 Process for preparing benzaldehydes BAYER AG (DE) 1991-06-05 EP disclosed
EP-0192242-B1 SUBSTITUTED AMINOPHENYLUREA DERIVATIVES TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1990-11-07 EP disclosed
US-4803223-A ANTITUMOR AGENTS TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1989-02-07 US disclosed
EP-0192242-A1 Substituted aminophenylurea derivatives TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1986-08-27 EP disclosed