Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | MGAM | O43451 | 3/20 | 0.43 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.43 |
| ▸ | SI | P14410 | 3/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20985958 | 0.83 | KDM4E (0.44) | NAMPTNPC1HCAR3MAPTHSD17B10 | |
| SCHEMBL26935472 | 0.83 | PKM (0.42) | NAMPTSMN1; SMN2HCAR3MAPTLMNA | |
| SCHEMBL26449157 | 0.83 | AR (0.49) | NAMPTRAB9AGAAMGAMAMY1A | |
| SCHEMBL26935726 | 0.81 | HCAR3 (0.40) | NAMPTHCAR3MAPTPOLB | |
| SCHEMBL4221495 | 0.80 | NAMPT (0.49) | NAMPTRAB9AGAANPC1MGAM | |
| SCHEMBL13523597 | 0.78 | HCAR3 (0.59) | NAMPTRAB9AGAANPC1MGAM | |
| SCHEMBL26442594 | 0.78 | HCAR3 (0.49) | NAMPTRAB9AGAANPC1MGAM | |
| SCHEMBL20986085 | 0.77 | ALDH1A1 (0.46) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL19911474 | 0.77 | NAMPT (0.49) | NAMPTRAB9AGAANPC1MGAM | |
| SCHEMBL17728250 | 0.77 | NAMPT (0.49) | NAMPTRAB9AGAANPC1MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4306520-A1 | THIOPHENE COMPOUND AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2024-01-17 | — | — | EP | disclosed |
| WO-2023179078-A1 | IMIDAZO [1,2-A] PYRAZINE OR PYRAZOLO [1,5-A] PYRIMIDINE DERIVATIVE AND USE THEREOF | 腾讯科技（深圳）有限公司 | 2023-09-28 | — | — | WO | disclosed |