Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.60 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GOT1 | P17174 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22118180 | 0.83 | EPHX2 (0.65) | EPHX2MCHR1POLBMEN1KMT2A | |
| SCHEMBL13480573 | 0.82 | EPHX2 (0.73) | EPHX2MCHR1POLBALDH1A1RAB9A | |
| SCHEMBL4117377 | 0.81 | EPHX2 (0.71) | EPHX2MCHR1ALDH1A1RAB9ALMNA | |
| SCHEMBL2643999 | 0.80 | EPHX2 (0.65) | EPHX2MCHR1POLBMEN1KMT2A | |
| SCHEMBL16449003 | 0.79 | ALDH1A1 (0.63) | KDM4EALDH1A1RAB9ALMNAMAPT | |
| SCHEMBL11778849 | 0.79 | EPHX2 (0.67) | EPHX2MCHR1POLBALDH1A1RAB9A | |
| SCHEMBL19358893 | 0.77 | EPHX2 (0.68) | EPHX2MCHR1POLBMEN1KMT2A | |
| SCHEMBL5314657 | 0.77 | EPHX2 (0.69) | EPHX2MCHR1POLBMEN1KMT2A | |
| SCHEMBL11555827 | 0.77 | EPHX2 (1.00) | EPHX2MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL19381603 | 0.77 | EPHX2 (0.77) | EPHX2MCHR1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040209928-A1 | Glucagon receptor antagonists/inverse agonists | ABBOTT LABORATORIES | 2004-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040209928-A1 | Glucagon receptor antagonists/inverse agonists | GLP1R, GPR119, GCGR | EPHX2 3048/4885MCHR1 193/4885POLB 4202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.