Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | FPR2 | P25090 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | GHSR | Q92847 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30099797 | 0.90 | ALDH1A1 (0.65) | ALDH1A1EPHX1HTTLMNANPSR1 | |
| SCHEMBL38660570 | 0.89 | EPHX1 (0.60) | ALDH1A1EPHX1HTTLMNANPSR1 | |
| SCHEMBL26661968 | 0.86 | ALDH1A1 (0.55) | ALDH1A1EPHX1HTTLMNANPSR1 | |
| SCHEMBL2451040 | 0.83 | EPHX1 (0.75) | ALDH1A1EPHX1HTTLMNAMAPT | |
| SCHEMBL13272561 | 0.82 | PKM (0.67) | ALDH1A1HTTLMNAMAPTRAB9A | |
| SCHEMBL10090175 | 0.82 | LMNA (0.63) | ALDH1A1EPHX1HTTLMNANPSR1 | |
| SCHEMBL26662004 | 0.80 | ALDH1A1 (0.50) | ALDH1A1EPHX1HTTLMNANPSR1 | |
| SCHEMBL4604785 | 0.80 | EPHX1 (0.87) | ALDH1A1EPHX1HTTLMNAMAPT | |
| SCHEMBL19489109 | 0.80 | EPHX2 (0.50) | ALDH1A1EPHX1HTTMAPTRAB9A | |
| SCHEMBL2644745 | 0.79 | EPHX2 (0.60) | ALDH1A1LMNAMAPTRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8952150-B2 | Prostaglandin transporter inhibitors and uses thereof | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2015-02-10 | — | — | US | disclosed |