SCHEMBL26449252

SCHEMBL26449252

Cc1ccc(C(OC(=O)C2CCCCN2C(=O)OCC2c3ccccc3-c3ccccc32)(c2ccccc2)c2ccccc2Cl)cc1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ FABP7 O15540 1/20 0.38
▸ FABP5 Q01469 1/20 0.38
▸ TSHR P16473 1/20 0.35
▸ FKBP1A P62942 12/20 0.35
▸ GFER P55789 1/20 0.34
▸ KDM4E B2RXH2 1/20 0.34
▸ MEN1 O00255 2/20 0.34
▸ KMT2A Q03164 2/20 0.34
▸ CTSB P07858 1/20 0.33
▸ CTSS P25774 1/20 0.33
▸ CTSK P43235 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24579905 0.89 FABP7 (0.37) FABP7FABP5FKBP1A
SCHEMBL25657678 0.88 FABP7 (0.36) FABP7FABP5TSHR
SCHEMBL25657679 0.85 FABP7 (0.36) FABP7FABP5GFERMEN1KMT2A
SCHEMBL28773187 0.83 FABP7 (0.39) FABP7FABP5
SCHEMBL29696667 0.83 ALDH1A1 (0.41) FABP7FABP5FKBP1A
SCHEMBL26448326 0.80 PRCP (0.40) —
SCHEMBL25657668 0.80 FABP5 (0.38) FABP7FABP5KMT2ACTSBCTSS
SCHEMBL28773174 0.79 FABP5 (0.38) FABP7FABP5
SCHEMBL25658698 0.79 FFAR2 (0.36) FABP7FABP5
SCHEMBL25658700 0.79 FFAR2 (0.36) FABP7FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230135758-A1 ELONGATION FACTOR 1-ALPHA INHIBITORS AND USES THEREOF UNIV CALIFORNIA (US) 2023-05-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230135758-A1 ELONGATION FACTOR 1-ALPHA INHIBITORS AND USES THEREOF EEF1A1, EEF1B2, EEF1G FABP7 3324/4885FABP5 3327/4885TSHR 4402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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