Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2647429 | 0.81 | RET (0.42) | RETCNR1SCN9ASYKGAA | |
| SCHEMBL2648414 | 0.80 | CNR1 (0.49) | RETCNR1SYKALDH1A1GAA | |
| SCHEMBL2644088 | 0.80 | MEN1 (0.46) | RETCNR1ALDH1A1MAPTMEN1 | |
| SCHEMBL15606453 | 0.79 | CNR1 (0.56) | RETCNR1SYKALDH1A1MAPT | |
| SCHEMBL30103987 | 0.79 | CNR1 (0.56) | RETCNR1SYKALDH1A1MAPT | |
| SCHEMBL2643153 | 0.76 | CNR1 (0.40) | CNR1SYKALDH1A1GAAMAPT | |
| SCHEMBL6797326 | 0.76 | CNR1 (0.46) | RETCNR1SYKHPGDPIK3CD | |
| SCHEMBL27354841 | 0.76 | RECQL (0.53) | SYKALDH1A1GAAMAPTKDM4E | |
| SCHEMBL10064753 | 0.76 | CNR1 (0.54) | RETCNR1ALDH1A1GAAMAPT | |
| SCHEMBL29871321 | 0.76 | CNR1 (0.54) | RETCNR1ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1164134-A1 | Benzimidazole compounds and their use as modulators of the GABA A receptor complex | NEUROSEARCH A/S (DK) | 2001-12-19 | — | — | EP | disclosed |
| CN-1072669-C | Benzimidazole compounds and their use as GABAAUse of receptor complex modulators | NEURORES AS (DK) | 2001-10-10 | — | — | CN | disclosed |
| US-5922724-A | Benzimidazole compounds and their use as modulators of the GABA a receptor complex | NEUROSEARCH A/S (DK) | 1999-07-13 | — | — | US | disclosed |
| CN-1182427-A | Benzimidazole compounds and their use as modulators of GABA receptor complexes | NEUROSEARCH AS (DK) | 1998-05-20 | — | — | CN | disclosed |
| EP-0821684-A1 | BENZIMIDAZOLE COMPOUNDS AND THEIR USE AS MODULATORS OF THE GABA A? RECEPTOR COMPLEX | NEUROSEARCH A/S (DK) | 1998-02-04 | — | — | EP | disclosed |
| WO-1996033194-A1 | BENZIMIDAZOLE COMPOUNDS AND THEIR USE AS MODULATORS OF THE GABA A RECEPTOR COMPLEX | NEUROSEARCH A/S (DK) | 1996-10-24 | — | — | WO | disclosed |