Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 3/20 | 0.45 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2644119 | 0.81 | HTT (0.50) | RECQLTSHRHTTALDH1A1HPGD | |
| SCHEMBL2645152 | 0.76 | RET (0.45) | ALDH1A1HPGDMAPTSYKMEN1 | |
| SCHEMBL27359055 | 0.74 | RECQL (0.62) | RECQLTSHRHTTALDH1A1HPGD | |
| SCHEMBL29833503 | 0.73 | TSHR (0.54) | RECQLTSHRHTTALDH1A1HPGD | |
| SCHEMBL2643153 | 0.73 | CNR1 (0.40) | ALDH1A1HPGDMAPTEGFRSYK | |
| SCHEMBL219238 | 0.71 | RECQL (1.00) | RECQLTSHRHTTALDH1A1HPGD | |
| SCHEMBL8057745 | 0.70 | MAPT (0.68) | RECQLTSHRHTTALDH1A1HPGD | |
| SCHEMBL2624598 | 0.69 | NPC1 (0.56) | RECQLTSHRHTTALDH1A1HPGD | |
| SCHEMBL7298693 | 0.69 | MAPT (0.59) | RECQLTSHRHTTALDH1A1HPGD | |
| SCHEMBL1764786 | 0.69 | MAPT (0.70) | HTTALDH1A1HPGDMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1072669-C | Benzimidazole compounds and their use as GABAAUse of receptor complex modulators | NEURORES AS (DK) | 2001-10-10 | — | — | CN | disclosed |
| CN-1182427-A | Benzimidazole compounds and their use as modulators of GABA receptor complexes | NEUROSEARCH AS (DK) | 1998-05-20 | — | — | CN | disclosed |