Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | CPB1 | P15086 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26452643 | 1.00 | CHRM5 (0.36) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL26452546 | 1.00 | CHRM5 (0.36) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL26452696 | 0.85 | CPB1 (0.45) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL26451281 | 0.85 | PDE4B (0.44) | CHRM4CYP2C9CYP2C19PIK3CDGRIN2B | |
| SCHEMBL26451300 | 0.85 | PDE4B (0.44) | CHRM4CYP2C9CYP2C19PIK3CDGRIN2B | |
| SCHEMBL26451317 | 0.85 | PDE4B (0.44) | CHRM4CYP2C9CYP2C19PIK3CDGRIN2B | |
| SCHEMBL18845641 | 0.82 | ALDH1A1 (0.43) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL19655862 | 0.82 | ALDH1A1 (0.43) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL21484546 | 0.82 | ALDH1A1 (0.43) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL19655812 | 0.82 | ALDH1A1 (0.43) | CHRM5CHRM1CHRM3CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230139156-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF UPADACITINIB | CURIA SPAIN, S.A.U. (ES) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230139156-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF UPADACITINIB | CDK19, CDK11B, CDK9 | CHRM5 4853/4885CHRM1 4778/4885CHRM3 4834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.