SCHEMBL23228071

SCHEMBL23228071

C1=CC(c2ccc(-c3ccccc3)cc2)CC(n2c3ccccc3c3cc(-c4ccc5c(c4)c4ccccc4n5-c4cccc5ccccc45)ccc32)=C1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSPO P30536 1/20 0.31
HDAC4 P56524 1/20 0.31
EGFR P00533 1/20 0.31
ERBB2 P04626 1/20 0.31
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
PKM P14618 1/20 0.30
HPGD P15428 1/20 0.30
HSD17B10 Q99714 1/20 0.30
HTR6 P50406 1/20 0.30
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26178246 0.87 L3MBTL1 (0.41) TSPOHDAC4ALDH1A1MAPT
SCHEMBL21300839 0.85 KDM4E (0.36) TSPOHDAC4
SCHEMBL26456567 0.85 HDAC4 (0.41) TSPOHDAC4
SCHEMBL20077874 0.84 HDAC4 (0.41) TSPOHDAC4
SCHEMBL5028223 0.83 KDM4E (0.36) TSPOHDAC4
SCHEMBL19452632 0.83 HDAC4 (0.35) TSPOHDAC4
SCHEMBL23312790 0.80 HDAC4 (0.30) HDAC4
SCHEMBL16152506 0.80 TSPO (0.42) TSPOALDH1A1HPGDHTR6CNR1
SCHEMBL24232503 0.80 ALDH1A1 (0.32) ALDH1A1MAPTPKMHPGDHSD17B10
SCHEMBL25117363 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021071248-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DIODE COMPRISING SAME, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DIODE, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING DIODE 엘티소재주식회사 2021-04-15 WO disclosed