Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26459782 | 1.00 | ALDH1A1 (0.35) | ALDH1A1HPGDHRH3GABBR2GABBR1 | |
| SCHEMBL26459778 | 0.97 | ALDH1A1 (0.35) | ALDH1A1HPGDHRH3GABBR2GABBR1 | |
| SCHEMBL25522724 | 0.96 | LMNA (0.39) | LMNAMAPTNPC1TP53 | |
| SCHEMBL26459763 | 0.95 | ALDH1A1 (0.36) | ALDH1A1HPGDGABBR2GABBR1LMNA | |
| SCHEMBL29478052 | 0.91 | SMN1; SMN2 (0.37) | ALDH1A1HPGDGABBR2GABBR1LMNA | |
| SCHEMBL493787 | 0.91 | SMN1; SMN2 (0.37) | ALDH1A1HPGDGABBR2GABBR1LMNA | |
| SCHEMBL27334072 | 0.91 | LMNA (0.36) | ALDH1A1HRH3LMNAMAPTMEN1 | |
| SCHEMBL30450985 | 0.91 | LMNA (0.36) | ALDH1A1HRH3LMNAMAPTMEN1 | |
| SCHEMBL26459777 | 0.91 | ALDH1A1 (0.36) | ALDH1A1HPGDGABBR2GABBR1KDM4E | |
| SCHEMBL39521 | 0.90 | ALDH1A1 (0.36) | ALDH1A1HPGDGABBR2GABBR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230127329-A1 | LACTONE COMPOUND | FUJIFILM CORPORATION (JP) | 2023-04-27 | — | — | US | disclosed |
| US-20230127329-A1 | LACTONE COMPOUND | FUJIFILM CORPORATION (JP) | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230127329-A1 | LACTONE COMPOUND | LANCL1, GPX1, LOXL1 | ALDH1A1 92/4885HPGD 401/4885HRH3 4728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.