Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 5/20 | 0.52 |
| ▸ | CLK2 | P49760 | 2/20 | 0.49 |
| ▸ | CLK3 | P49761 | 2/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.48 |
| ▸ | FABP6 | P51161 | 1/20 | 0.47 |
| ▸ | WNT1 | P04628 | 3/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | MASP2 | O00187 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30494494 | 1.00 | ABL1 (0.52) | ABL1CLK2CLK3DYRK1ACYP11B1 | |
| SCHEMBL5680411 | 0.81 | TRPA1 (0.52) | ABL1FABP6MASP2MEN1ALDH1A1 | |
| SCHEMBL26463643 | 0.80 | CYP11B1 (0.55) | ABL1CLK2CLK3DYRK1ACYP11B1 | |
| SCHEMBL30494300 | 0.80 | CYP11B1 (0.55) | ABL1CLK2CLK3DYRK1ACYP11B1 | |
| SCHEMBL16848371 | 0.77 | JAK2 (0.50) | FABP6MASP2MEN1ALDH1A1NUDT1 | |
| SCHEMBL30494142 | 0.76 | ABL1 (0.56) | ABL1CLK2CLK3DYRK1ACYP11B1 | |
| SCHEMBL26100602 | 0.76 | ABL1 (0.56) | ABL1CLK2CLK3DYRK1ACYP11B1 | |
| SCHEMBL14395420 | 0.75 | ALDH1A1 (0.52) | CLK2CLK3DYRK1ACYP11B1CYP11B2 | |
| SCHEMBL30494163 | 0.74 | CLK2 (0.48) | ABL1CLK2CLK3DYRK1ACYP11B1 | |
| SCHEMBL26463103 | 0.74 | ABL1 (0.48) | ABL1CLK2CLK3DYRK1ACYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118176181-A | SARM1 modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-06-11 | — | — | CN | disclosed |
| WO-2023072026-A1 | SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-05-04 | — | — | WO | disclosed |