Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23823763 | 0.82 | NFE2L2 (0.52) | NFE2L2HCAR2KEAP1ALDH1A1ALOX15 | |
| SCHEMBL3022767 | 0.73 | NFE2L2 (0.60) | NFE2L2HCAR2KEAP1ALDH1A1ALOX15 | |
| SCHEMBL1881404 | 0.73 | NFE2L2 (0.60) | NFE2L2HCAR2KEAP1ALDH1A1ALOX15 | |
| SCHEMBL901299 | 0.73 | NFE2L2 (0.52) | NFE2L2HCAR2KEAP1ALDH1A1ALOX15 | |
| Dimethyl Fumarate SCHEMBL29110379 | 0.72 | NFE2L2 (0.77) | NFE2L2HCAR2KEAP1ALDH1A1ALOX15 | |
| SCHEMBL2418087 | 0.71 | NFE2L2 (0.57) | NFE2L2HCAR2KEAP1ALDH1A1ALOX15 | |
| SCHEMBL10350565 | 0.71 | NFE2L2 (0.57) | NFE2L2HCAR2KEAP1ALDH1A1ALOX15 | |
| SCHEMBL321329 | 0.71 | NFE2L2 (0.57) | NFE2L2HCAR2KEAP1ALDH1A1ALOX15 | |
| SCHEMBL321328 | 0.71 | NFE2L2 (0.57) | NFE2L2HCAR2KEAP1ALDH1A1ALOX15 | |
| Ammonia Solution, Strong SCHEMBL27555207 | 0.71 | NFE2L2 (0.50) | NFE2L2HCAR2KEAP1ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230139593-A1 | TREATMENT OF DISORDERS ASSOCIATED WITH OXIDATIVE STRESS AND COMPOUNDS FOR SAME | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2023-05-04 | — | — | US | disclosed |
| US-20230139593-A1 | TREATMENT OF DISORDERS ASSOCIATED WITH OXIDATIVE STRESS AND COMPOUNDS FOR SAME | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230139593-A1 | TREATMENT OF DISORDERS ASSOCIATED WITH OXIDATIVE STRESS AND COMPOUNDS FOR SAME | GPX4, TXNRD2, TXN2 | NFE2L2 34/4885HCAR2 1367/4885KEAP1 87/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.