Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27566866 | 0.75 | CYP1A2 (0.30) | CYP1A2TSHRNFKB1MAOAMAOB | |
| SCHEMBL6222074 | 0.75 | CHRM2 (0.31) | CA2NFKB1 | |
| SCHEMBL21802925 | 0.75 | ALDH1A1 (0.32) | — | |
| SCHEMBL52 | 0.74 | CA2 (0.35) | CA2 | |
| SCHEMBL27623481 | 0.74 | CA2 (0.35) | CA2 | |
| SCHEMBL5477482 | 0.74 | — | — | |
| Urea SCHEMBL28253601 | 0.73 | ALDH1A1 (0.38) | CA2 | |
| Hydrochloric Acid SCHEMBL8958370 | 0.72 | CA2 (0.33) | CA2 | |
| SCHEMBL3945657 | 0.72 | CA2 (0.33) | CA2 | |
| Hydrogen Peroxide SCHEMBL2051538 | 0.72 | CA2 (0.33) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140823-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039088-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-07-06 | — | — | WO | disclosed |