SCHEMBL2646513

SCHEMBL2646513

CCOP(=O)(OCC)C(F)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.43
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
TSHR P16473 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.37
GAA P10253 3/20 0.37
MAPT P10636 1/20 0.36
TP53 P04637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
PPARD Q03181 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propene SCHEMBL28006036 0.91 POLB (0.38) POLBCYP3A4CYP2C9CYP2C19TSHR
SCHEMBL27501838 0.83 POLB (0.43) POLBCYP3A4CYP2C9CYP2C19TSHR
SCHEMBL2992966 0.83 CYP3A4 (0.40) POLBCYP3A4CYP2C9CYP2C19TSHR
SCHEMBL14671697 0.81 CYP3A4 (0.42) POLBCYP3A4CYP2C9CYP2C19TSHR
SCHEMBL14671389 0.81 LMNA (0.39) POLBCYP3A4CYP2C9CYP2C19TSHR
SCHEMBL9617315 0.81 LMNA (0.39) POLBCYP3A4CYP2C9CYP2C19TSHR
SCHEMBL365852 0.81 CYP3A4 (0.39) POLBCYP3A4CYP2C9CYP2C19TSHR
SCHEMBL16761024 0.79 CYP3A4 (0.41) POLBCYP3A4CYP2C9CYP2C19TSHR
SCHEMBL24142138 0.78 CYP3A4 (0.37) POLBCYP3A4CYP2C9CYP2C19TSHR
SCHEMBL17937995 0.77 POLB (0.46) POLBCYP3A4CYP2C9CYP2C19TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2882030-B1 NON-AQUEOUS ELECTROLYTE AND ENERGY STORAGE DEVICE USING THE SAME UBE INDUSTRIES (JP) 2017-06-21 EP claimed
EP-2698859-B1 NON-AQUEOUS ELECTROLYTIC SOLUTION AND ELECTRICITY-STORAGE DEVICE USING THE SAME UBE INDUSTRIES (JP) 2016-07-27 EP claimed
EP-2882030-A1 NON-AQUEOUS ELECTROLYTE AND POWER STORAGE DEVICE USING SAME Ube Industries, Ltd. (JP) 2015-06-10 EP claimed
CN-101768114-B Synthesis method of 4-substituted-3-fluorine-2-quinolone UNIV SOUTHWEST 2011-07-20 CN claimed
CN-120117999-A Fluorotranilast derivatives and medical application thereof 中国药科大学 2025-06-10 CN disclosed
US-20250084062-A1 SUBSTITUTED QUINOLINE DERIVATIVE ASTELLAS PHARMA INC. (JP) 2025-03-13 US disclosed
EP-4506343-A1 HETEROARYL DERIVATIVE AND USE THEREOF Voronoi Inc. (KR) 2025-02-12 EP disclosed
US-20240383923-A1 HETEROARYL DERIVATIVE AND USE THEREOF VORONOI INC. (KR) 2024-11-21 US disclosed
CN-118946557-A Heteroaryl derivatives and uses thereof 株式会社沃若诺伊 2024-11-12 CN disclosed
CN-118488952-A Substituted quinoline derivatives 安斯泰来制药有限公司 2024-08-13 CN disclosed
US-20240246940-A1 HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF VORONOI INC. (KR) 2024-07-25 US disclosed
US-12018023-B2 Heterocondensed pyridones compounds and their use as IDH inhibitors NERVIANO MEDICAL SCIENCES S.R.L. (IT) 2024-06-25 US disclosed
US-6555556-B1 N-(4-(1-acetimidoylpiperidin-4-yl)oxyphenyl)-N-((E)-3-(3 -amidinophenyl)-2-methyl-2-propenyl)sulfamoylacetic acid dihydrochloride for example; factor Xa inhibitors SANKYO COMPANY, LIMITED (JP) 2003-04-29 US disclosed
EP-1245564-A1 BENZAMIDINE DERIVATIVES Sankyo Company, Limited (JP) 2002-10-02 EP disclosed
EP-0402246-B1 Thiazolylalkoxyacrylates, process for their preparation, their use as fungicides and intermediates in their preparation ROUSSEL UCLAF (FR) 1994-08-24 EP disclosed
EP-0601573-A1 Alpha-phosphonocarboxylate squalene synthetase inhibitors and method BRISTOL-MYERS SQUIBB COMPANY (US) 1994-06-15 EP disclosed
US-5312814-A Antilipemic agents or anticholesterol agents BRISTOL-MYERS SQUIBB CO. (US) 1994-05-17 US disclosed
EP-0402246-A1 Thiazolylalkoxyacrylates, process for their preparation, their use as fungicides and intermediates in their preparation ROUSSEL-UCLAF (FR) 1990-12-12 EP disclosed
US-4906663-A 6-fluoroprostaglandins ASAHI GLASS COMPANY, LTD. (JP) 1990-03-06 US disclosed
EP-0312055-A2 6-Fluoroprostaglandins ASAHI GLASS COMPANY LTD. (JP) 1989-04-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240246940-A1 HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF ERBB2, EGFR, ERBB3 POLB 4412/4885CYP3A4 1028/4885CYP2C9 1493/4885
US-12018023-B2 Heterocondensed pyridones compounds and their use as IDH inhibitors IDH1, IDH2, IDH3A POLB 1098/4885CYP3A4 916/4885CYP2C9 750/4885
US-20250084062-A1 SUBSTITUTED QUINOLINE DERIVATIVE CHRNA4, CHRNA2, CHRNA5 POLB 4491/4885CYP3A4 1553/4885CYP2C9 3729/4885
US-20240383923-A1 HETEROARYL DERIVATIVE AND USE THEREOF ERBB2, ERBB3, EGFR POLB 3671/4885CYP3A4 249/4885CYP2C9 383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.