SCHEMBL2646530

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1624945	0.95	MCL1 (0.49)	MCL1MAPTALOX15HTTHBB
	SCHEMBL8924501	0.82	MCL1 (0.44)	MCL1MAPTALOX15HTTHBB
	SCHEMBL2645803	0.74	FAAH (0.49)	CES2CES1ALDH1A1L3MBTL1POLB
	SCHEMBL2569683	0.74	KMT2A (0.39)	MCL1MAPTALOX15HTTHBB
	SCHEMBL7295695	0.71	MCL1 (0.44)	MCL1MAPTSLC18A3ALDH1A1HTR2A
	SCHEMBL9041510	0.71	SRD5A2 (0.47)	MCL1SLC18A3ALDH1A1HTR2ACPB1
	SCHEMBL27848887	0.71	MCL1 (0.51)	MCL1MAPTALOX15HTTHBB
	SCHEMBL7373256	0.71	CES2 (0.43)	MAPTALOX15CES2CES1ALDH1A1
	SCHEMBL5231305	0.71	—	—
	SCHEMBL917888	0.71	—	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.