Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26465696 | 0.87 | CACNA1H (0.44) | ALDH1A1KDM4EDRD4TMEM97SIGMAR1 | |
| SCHEMBL26465823 | 0.86 | HPGD (0.52) | KDM4EL3MBTL1HPGDKMT2AMEN1 | |
| SCHEMBL26466596 | 0.82 | CACNA1H (0.40) | ALDH1A1KDM4EDRD4TMEM97SIGMAR1 | |
| SCHEMBL26465821 | 0.79 | CACNA1H (0.41) | WNT3A | |
| SCHEMBL26466608 | 0.78 | CACNA1H (0.42) | ALDH1A1KDM4EDRD4TMEM97SIGMAR1 | |
| SCHEMBL26465708 | 0.77 | CACNA1H (0.49) | ALDH1A1KDM4EL3MBTL1KMT2AMEN1 | |
| SCHEMBL26465703 | 0.76 | CACNA1H (0.40) | ALDH1A1KDM4EDRD4TMEM97SIGMAR1 | |
| SCHEMBL26083795 | 0.75 | EPHX2 (0.48) | ALDH1A1KDM4EDRD4TMEM97SIGMAR1 | |
| SCHEMBL26465692 | 0.75 | CACNA1H (0.45) | ALDH1A1KDM4EL3MBTL1HPGDGLA | |
| SCHEMBL26465812 | 0.73 | CACNA1H (0.47) | ALDH1A1KDM4EHPGDGLATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192669-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A PIPERAZINE OR 1,4-DIAZEPANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |