Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26465708 | 0.90 | CACNA1H (0.49) | CACNA1HALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL26465692 | 0.88 | CACNA1H (0.45) | CACNA1HALDH1A1KDM4EL3MBTL1HPGD | |
| SCHEMBL26466596 | 0.88 | CACNA1H (0.40) | CACNA1HALDH1A1KDM4EHPGDGLA | |
| SCHEMBL26465812 | 0.87 | CACNA1H (0.47) | CACNA1HALDH1A1KDM4EHPGDGLA | |
| SCHEMBL26465816 | 0.87 | ALDH1A1 (0.39) | ALDH1A1KDM4EL3MBTL1HPGDGLA | |
| SCHEMBL26465821 | 0.87 | CACNA1H (0.41) | CACNA1H | |
| SCHEMBL26464502 | 0.85 | CACNA1H (0.50) | CACNA1HALDH1A1KDM4EHPGDDRD4 | |
| SCHEMBL26465703 | 0.85 | CACNA1H (0.40) | CACNA1HALDH1A1KDM4EL3MBTL1HPGD | |
| SCHEMBL26466608 | 0.84 | CACNA1H (0.42) | CACNA1HALDH1A1KDM4EHPGDGLA | |
| SCHEMBL26465699 | 0.84 | HPGD (0.55) | CACNA1HALDH1A1KDM4EL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192669-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A PIPERAZINE OR 1,4-DIAZEPANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |