Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | CXCR6 | O00574 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26465692 | 0.91 | CACNA1H (0.45) | CACNA1HALDH1A1KDM4EL3MBTL1KMT2A | |
| SCHEMBL26465696 | 0.90 | CACNA1H (0.44) | CACNA1HALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL26465996 | 0.89 | L3MBTL1 (0.52) | CACNA1HALDH1A1KDM4EL3MBTL1KMT2A | |
| SCHEMBL26466777 | 0.87 | ALDH1A1 (0.45) | CACNA1HALDH1A1KDM4EL3MBTL1KMT2A | |
| SCHEMBL26465699 | 0.86 | HPGD (0.55) | CACNA1HALDH1A1KDM4EL3MBTL1KMT2A | |
| SCHEMBL26465810 | 0.85 | CACNA1H (0.47) | CACNA1HALDH1A1KDM4EHTTMAPT | |
| SCHEMBL26465812 | 0.85 | CACNA1H (0.47) | CACNA1HALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL26465825 | 0.85 | ALDH1A1 (0.44) | CACNA1HALDH1A1KDM4EL3MBTL1KMT2A | |
| SCHEMBL26465811 | 0.83 | ALDH1A1 (0.49) | CACNA1HALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL26465562 | 0.82 | SMN1; SMN2 (0.57) | CACNA1HALDH1A1KDM4EKMT2ACXCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192669-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A PIPERAZINE OR 1,4-DIAZEPANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |