Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26464489 | 0.90 | CACNA1H (0.38) | CACNA1HALDH1A1KDM4EGLATDP1 | |
| SCHEMBL26465693 | 0.90 | CACNA1H (0.41) | CACNA1HALDH1A1KDM4EHPGDGLA | |
| SCHEMBL26465825 | 0.90 | ALDH1A1 (0.44) | CACNA1HALDH1A1KDM4EL3MBTL1MEN1 | |
| SCHEMBL26466912 | 0.90 | CACNA1H (0.38) | CACNA1HALDH1A1KDM4EHPGDGLA | |
| SCHEMBL26465818 | 0.88 | CACNA1H (0.42) | CACNA1HALDH1A1KDM4EHPGDGLA | |
| SCHEMBL26465817 | 0.87 | CACNA1H (0.38) | CACNA1HEPHX2LMNAWNT3A | |
| SCHEMBL26465696 | 0.85 | CACNA1H (0.44) | CACNA1HALDH1A1KDM4EHPGDGLA | |
| SCHEMBL26465688 | 0.85 | HPGD (0.53) | CACNA1HALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL26465813 | 0.85 | MAPT (0.43) | CACNA1HALDH1A1KDM4EHPGDGLA | |
| SCHEMBL26465563 | 0.83 | CACNA1H (0.42) | CACNA1HALDH1A1KDM4EEPHX2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192669-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A PIPERAZINE OR 1,4-DIAZEPANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |