Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 8/20 | 0.53 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26466415 | 1.00 | CACNA1H (0.53) | CACNA1HGRM4MEN1KMT2ALTA4H | |
| SCHEMBL26466909 | 0.89 | CACNA1H (0.44) | CACNA1HMEN1KMT2ALTA4HMCHR1 | |
| SCHEMBL26465080 | 0.88 | CACNA1H (0.56) | CACNA1HGRM4MEN1KMT2ACXCR6 | |
| SCHEMBL26466915 | 0.87 | CACNA1H (0.46) | CACNA1HMEN1KMT2ALTA4HMCHR1 | |
| SCHEMBL26466903 | 0.85 | CACNA1H (0.50) | CACNA1HMEN1KMT2ALTA4HALDH1A1 | |
| SCHEMBL26466594 | 0.85 | HPGD (0.49) | CACNA1HKMT2AMCHR1ALDH1A1 | |
| SCHEMBL26466250 | 0.85 | HPGD (0.49) | CACNA1HKMT2AMCHR1ALDH1A1 | |
| SCHEMBL26466243 | 0.85 | HPGD (0.49) | CACNA1HKMT2AMCHR1ALDH1A1 | |
| SCHEMBL26466919 | 0.85 | CACNA1H (0.42) | CACNA1HMEN1KMT2ALTA4HMCHR1 | |
| SCHEMBL26466389 | 0.84 | CACNA1H (0.40) | CACNA1HMEN1KMT2ALTA4HALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192669-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A PIPERAZINE OR 1,4-DIAZEPANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |