Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26466097 | 0.89 | CACNA1H (0.45) | CACNA1HHPGDKMT2AMAPTMEN1 | |
| SCHEMBL26466594 | 0.88 | HPGD (0.49) | CACNA1HHPGDKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL26466250 | 0.88 | HPGD (0.49) | CACNA1HHPGDKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL26466243 | 0.88 | HPGD (0.49) | CACNA1HHPGDKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL26466922 | 0.86 | CACNA1H (0.41) | CACNA1HLTA4HMAPTLMNAHTT | |
| SCHEMBL26466233 | 0.85 | CACNA1H (0.53) | CACNA1HKMT2ALTA4HMEN1MCHR1 | |
| SCHEMBL26466415 | 0.85 | CACNA1H (0.53) | CACNA1HKMT2ALTA4HMEN1MCHR1 | |
| SCHEMBL26467004 | 0.84 | CACNA1H (0.36) | CACNA1HLTA4H | |
| SCHEMBL26466926 | 0.83 | ALDH1A1 (0.47) | HPGDKMT2AMAPTMEN1LMNA | |
| SCHEMBL26466909 | 0.82 | CACNA1H (0.44) | CACNA1HKMT2ALTA4HMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192669-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A PIPERAZINE OR 1,4-DIAZEPANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |