Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26466415 | 0.89 | CACNA1H (0.53) | CACNA1HMEN1KMT2AALDH1A1RECQL | |
| SCHEMBL26466233 | 0.89 | CACNA1H (0.53) | CACNA1HMEN1KMT2AALDH1A1RECQL | |
| SCHEMBL26466915 | 0.88 | CACNA1H (0.46) | CACNA1HMEN1KMT2AALDH1A1LTA4H | |
| SCHEMBL26466926 | 0.83 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1CYP2D6MAPT | |
| SCHEMBL26466594 | 0.82 | HPGD (0.49) | CACNA1HKMT2AALDH1A1MCHR1MAPT | |
| SCHEMBL26466916 | 0.82 | SIGMAR1 (0.42) | CACNA1HLTA4HDRD4DRD3MAPT | |
| SCHEMBL26466243 | 0.82 | HPGD (0.49) | CACNA1HKMT2AALDH1A1MCHR1MAPT | |
| SCHEMBL26466250 | 0.82 | HPGD (0.49) | CACNA1HKMT2AALDH1A1MCHR1MAPT | |
| SCHEMBL26466919 | 0.82 | CACNA1H (0.42) | CACNA1HMEN1KMT2AALDH1A1LTA4H | |
| SCHEMBL26466621 | 0.81 | CACNA1H (0.47) | CACNA1HALDH1A1RECQLLTA4HBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192669-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A PIPERAZINE OR 1,4-DIAZEPANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |