Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26466002 | 0.83 | SIGMAR1 (0.50) | SIGMAR1HPGDCYP3A4CYP2C19GAA | |
| SCHEMBL26466918 | 0.81 | CACNA1H (0.35) | GAAKMT2ACACNA1H | |
| SCHEMBL931682 | 0.80 | SIGMAR1 (0.46) | SIGMAR1HPGDCYP3A4CYP2C19CHRM5 | |
| SCHEMBL2605751 | 0.76 | HPGD (0.53) | HPGDCYP3A4KMT2ANPSR1EPHX1 | |
| SCHEMBL26466763 | 0.74 | CACNA1H (0.51) | KMT2ANPSR1CACNA1H | |
| SCHEMBL26466599 | 0.72 | CACNA1H (0.70) | KMT2ACACNA1H | |
| SCHEMBL26466764 | 0.72 | CACNA1H (0.55) | KMT2ANPSR1CACNA1H | |
| SCHEMBL1555258 | 0.71 | HPGD (0.49) | SIGMAR1HPGDCYP3A4CYP2C19CHRM5 | |
| SCHEMBL12829197 | 0.71 | SMN1; SMN2 (0.47) | HPGDGAAKMT2ANPSR1EPHX1 | |
| SCHEMBL26466613 | 0.69 | CACNA1H (0.52) | KMT2AL3MBTL1CACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192669-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A PIPERAZINE OR 1,4-DIAZEPANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |