Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 9/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26465984 | 0.87 | CACNA1H (0.40) | CACNA1HKMT2A | |
| SCHEMBL26466767 | 0.81 | SIGMAR1 (0.45) | CACNA1HKMT2AGAA | |
| SCHEMBL26466002 | 0.66 | SIGMAR1 (0.50) | CACNA1HKMT2AGAA | |
| SCHEMBL26466996 | 0.66 | CACNA1H (0.41) | CACNA1H | |
| SCHEMBL26466207 | 0.65 | CACNA1H (0.46) | CACNA1HKMT2AEPHX2 | |
| SCHEMBL26466598 | 0.65 | CACNA1H (0.46) | CACNA1HKMT2AEPHX2 | |
| SCHEMBL931682 | 0.65 | SIGMAR1 (0.46) | KMT2AEPHX2 | |
| SCHEMBL26466763 | 0.65 | CACNA1H (0.51) | CACNA1HKMT2A | |
| SCHEMBL26466599 | 0.63 | CACNA1H (0.70) | CACNA1HKMT2AEPHX2 | |
| SCHEMBL26466764 | 0.63 | CACNA1H (0.55) | CACNA1HKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192669-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A PIPERAZINE OR 1,4-DIAZEPANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |