Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26466996 | 0.89 | CACNA1H (0.41) | CACNA1HALDH1A1KDM4EANO1LTA4H | |
| SCHEMBL26466777 | 0.88 | ALDH1A1 (0.45) | CACNA1HALDH1A1KDM4EANO1WNT3A | |
| SCHEMBL26466921 | 0.85 | CACNA1H (0.41) | CACNA1HTSHRHTTLTA4HKMT2A | |
| SCHEMBL26466922 | 0.84 | CACNA1H (0.41) | CACNA1HALDH1A1KDM4EWNT3ATSHR | |
| SCHEMBL26466617 | 0.82 | CACNA1H (0.67) | CACNA1HALDH1A1KDM4ELTA4HLMNA | |
| SCHEMBL26466913 | 0.82 | L3MBTL1 (0.48) | CACNA1HALDH1A1KDM4EHTTLTA4H | |
| SCHEMBL26466596 | 0.79 | CACNA1H (0.40) | CACNA1HALDH1A1KDM4EANO1HTT | |
| SCHEMBL26466613 | 0.78 | CACNA1H (0.52) | CACNA1HALDH1A1ANO1LTA4HMAPT | |
| SCHEMBL26466398 | 0.78 | CACNA1H (0.49) | CACNA1HALDH1A1ANO1LTA4H | |
| SCHEMBL26466390 | 0.78 | CACNA1H (0.49) | CACNA1HALDH1A1ANO1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192669-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A PIPERAZINE OR 1,4-DIAZEPANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |