Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CXCR6 | O00574 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26467004 | 0.89 | CACNA1H (0.36) | CACNA1HLTA4H | |
| SCHEMBL26465564 | 0.89 | CACNA1H (0.43) | CACNA1HALDH1A1KDM4ESMN1; SMN2CXCR6 | |
| SCHEMBL26466919 | 0.86 | CACNA1H (0.42) | CACNA1HALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL26466914 | 0.84 | L3MBTL1 (0.43) | CACNA1HALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL26466903 | 0.84 | CACNA1H (0.50) | CACNA1HALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL26466925 | 0.84 | CACNA1H (0.46) | CACNA1HALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL26466915 | 0.81 | CACNA1H (0.46) | CACNA1HALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL26466916 | 0.80 | SIGMAR1 (0.42) | CACNA1HMAPTTSHRLTA4H | |
| SCHEMBL26466912 | 0.80 | CACNA1H (0.38) | CACNA1HALDH1A1KDM4EMAPTLTA4H | |
| SCHEMBL26466415 | 0.79 | CACNA1H (0.53) | CACNA1HALDH1A1CXCR6LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192669-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A PIPERAZINE OR 1,4-DIAZEPANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |