Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30296581 | 1.00 | TRPM8 (0.36) | TRPM8MEN1KMT2AMLYCDTDP1 | |
| SCHEMBL568769 | 0.84 | PDK2 (0.40) | TRPM8MLYCDAGBL2GPBAR1CLK1 | |
| SCHEMBL14484964 | 0.83 | KDM4E (0.36) | MEN1KMT2AMLYCDTDP1CLK1 | |
| SCHEMBL24424181 | 0.79 | MLYCD (0.38) | TRPM8MEN1KMT2AMLYCDGPBAR1 | |
| SCHEMBL30133796 | 0.79 | MLYCD (0.38) | TRPM8MEN1KMT2AMLYCDGPBAR1 | |
| SCHEMBL2943288 | 0.79 | MLYCD (0.36) | TRPM8MEN1KMT2AMLYCDTDP1 | |
| SCHEMBL16632434 | 0.78 | NPSR1 (0.41) | AGBL2KEAP1PKM | |
| SCHEMBL30960730 | 0.78 | NPSR1 (0.41) | AGBL2KEAP1PKM | |
| SCHEMBL29560615 | 0.75 | AGBL2 (0.39) | AGBL2KEAP1PKM | |
| SCHEMBL22866557 | 0.75 | AGBL2 (0.39) | AGBL2KEAP1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916754-A | Heteroaromatic macrocyclic ether chemotherapeutic agents | 纽威伦特公司 | 2023-04-04 | — | — | CN | disclosed |