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SCHEMBL26468700

SCHEMBL26468700

c1ccc(-c2nc3ccc(N(c4ccc5c(ccc6cc(N(c7ccc8c(c7)OC(c7ccccc7)N8)c7cccc8ccccc78)ccc65)c4)c4cccc5ccccc45)cc3o2)cc1

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 16/20 0.33
▸ MAPT P10636 2/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ NPC1 O15118 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ ESR1 P03372 1/20 0.32
▸ ESR2 Q92731 1/20 0.32
▸ MGLL Q99685 1/20 0.31
▸ TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26196607 0.87 GPR119 (0.38) GPR119MAPTMEN1NPC1ALDH1A1
SCHEMBL26465655 0.85 MAPT (0.42) GPR119MAPTMEN1NPC1ALDH1A1
SCHEMBL26469094 0.81 — —
SCHEMBL26465683 0.79 MAPT (0.39) GPR119MAPTMEN1NPC1ALDH1A1
SCHEMBL26468721 0.79 GPR119 (0.31) GPR119
SCHEMBL23667867 0.76 ESR1 (0.44) GPR119MAPTMEN1NPC1ALDH1A1
SCHEMBL26468243 0.75 NPC1 (0.45) MAPTMEN1NPC1ALDH1A1RAB9A
SCHEMBL23667911 0.74 VSIR (0.41) GPR119MAPTMEN1NPC1ALDH1A1
SCHEMBL26468705 0.74 SMN1; SMN2 (0.46) GPR119MAPTMEN1NPC1ALDH1A1
SCHEMBL12267989 0.73 GPR119 (0.48) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023071073-A1 ARYLAMINE ORGANIC COMPOUND AND USE THEREOF 广州华睿光电材料有限公司 2023-05-04 — — WO disclosed