SCHEMBL264705

SCHEMBL264705

COc1cccc2c1CCCC2=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.54
ACHE P22303 1/20 0.51
MRGPRX4 Q96LA9 1/20 0.50
ABCB1 P08183 1/20 0.50
ADRB2 P07550 1/20 0.50
ADRB1 P08588 1/20 0.50
HTR1A P08908 1/20 0.50
ADRB3 P13945 1/20 0.50
TSHR P16473 1/20 0.50
SLC6A4 P31645 1/20 0.50
SIGMAR1 Q99720 1/20 0.50
BRAF P15056 1/20 0.50
ALDH1A1 P00352 3/20 0.49
KDM4E B2RXH2 3/20 0.49
HPGD P15428 2/20 0.49
MAPT P10636 2/20 0.48
NPSR1 Q6W5P4 1/20 0.48
LMNA P02545 1/20 0.47
POLB P06746 1/20 0.47
MEN1 O00255 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29802310 1.00 BRD4 (0.54) BRD4ACHEMRGPRX4ABCB1ADRB2
SCHEMBL14120635 0.96 ACHE (0.51) BRD4ACHEMRGPRX4ABCB1ADRB2
SCHEMBL165220 0.89 KDM4E (0.61) ACHEABCB1BRAFALDH1A1KDM4E
SCHEMBL29506042 0.89 KDM4E (0.61) ACHEABCB1BRAFALDH1A1KDM4E
SCHEMBL21821534 0.82 MRGPRX4 (0.54) BRD4MRGPRX4ABCB1ADRB2ADRB1
SCHEMBL15283161 0.81 TSHR (0.50) BRD4ACHEMRGPRX4ABCB1ADRB2
SCHEMBL5270656 0.81 MRGPRX4 (0.56) BRD4MRGPRX4ABCB1ADRB2ADRB1
SCHEMBL6635718 0.81 MEN1 (0.50) BRD4ACHEBRAFALDH1A1KDM4E
SCHEMBL14172820 0.81 BRD4 (0.47) BRD4ACHEMRGPRX4ABCB1ADRB2
SCHEMBL11805157 0.80 MRGPRX4 (0.52) BRD4ACHEMRGPRX4ABCB1ADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 563 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120118678-A Color-adjustable organic room-temperature phosphorescent material and preparation method and application thereof 江西科技师范大学 2025-06-10 CN claimed
CN-119930666-A Doped red organic room-temperature phosphorescent material based on red phosphorescent emitter and preparation method thereof 江西科技师范大学 2025-05-06 CN claimed
US-7074770-B1 Method of DNA vaccination SMITHKLINE BEECHAM CORPORATION (US) 2006-07-11 US claimed
US-6461417-B1 Ink compositions XEROX CORPORATION 2002-10-08 US claimed
EP-1107785-A1 METHOD OF DNA VACCINATION GLAXO GROUP LIMITED (GB) 2001-06-20 EP claimed
US-6117223-A Hot melt inks containing polyketones XEROX CORPORATION (US) 2000-09-12 US claimed
WO-2000012121-A1 METHOD OF DNA VACCINATION GLAXO GROUP LIMITED (GB) 2000-03-09 WO claimed
US-5663029-A DEVELOPMENT OF LATENT IMAGE, TRANSFERRING TO FORM RECORDING SHEETS, COATING A SUBSTRATE USING POLYMERS XEROX CORPORATION (US) 1997-09-02 US claimed
US-5618982-A SIMPLE INDUSTRIAL PROCESS OF CATALYZING IN PRESENCE OF METALLIC PHOSPHATES RHONE-POULENC CHIMIE (FR) 1997-04-08 US claimed
JP-57056494-A None JP disclosed
JP-59073539-A None JP disclosed
US-20250333371-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-10-30 US disclosed
EP-3956334-B1 COMPOUNDS FOR OPTICALLY ACTIVE DEVICES AMO Ireland (IE) 2025-09-24 EP disclosed
CN-120118678-A Color-adjustable organic room-temperature phosphorescent material and preparation method and application thereof 江西科技师范大学 2025-06-10 CN disclosed
US-4117230-A ANTIDIABETIC AGENTS PFIZER INC. (US) 1978-09-26 US disclosed
US-4101677-A Aminotetralins and use in inducing anesthesia ABBOTT LABORATORIES (US) 1978-07-18 US disclosed
US-4057582-A Aminotetralins and use in inducing anesthesia ABBOTT LABORATORIES (US) 1977-11-08 US disclosed
US-3991207-A TETRAHYDRONAPHTHYLAMINES AND L-3,4-DIHYDROXYPHENYL-ALANINE PFIZER INC. (US) 1976-11-09 US disclosed
US-3959480-A Polycyclic gamma-pyrone-3-carboxaldehyde derivatives WARNER-LAMBERT COMPANY (US) 1976-05-25 US disclosed
US-3936488-A Polycyclic dioxaborin complexes WARNER-LAMBERT COMPANY (US) 1976-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250333371-A1 COMPOUNDS SDHA, PYGB, SLC18A2 BRD4 3733/4885ACHE 31/4885MRGPRX4 2850/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.