Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.62 |
| ▸ | RARG | P13631 | 6/20 | 0.62 |
| ▸ | RARA | P10276 | 5/20 | 0.62 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.46 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.46 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | HNF4A | P41235 | 1/20 | 0.41 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417023 | 0.83 | RARB (0.71) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL9850154 | 0.80 | RARB (0.67) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL10556841 | 0.77 | RARB (1.00) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL10556851 | 0.77 | RARB (1.00) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL8702828 | 0.73 | RARB (0.59) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL2240683 | 0.73 | RARB (0.64) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL2240304 | 0.73 | RARB (0.76) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL13479198 | 0.73 | RARB (0.58) | RARBRARGRARACYP26A1CYP26B1 | |
| Hydrochloric Acid SCHEMBL9133279 | 0.72 | RARB (0.74) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL16744298 | 0.72 | RARB (0.73) | RARBRARGRARARXRACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230346743-A1 | COMBINATION CANCER THERAPIES | UNIV OKLAHOMA (US) | 2023-11-02 | — | — | US | disclosed |
| US-20230139842-A1 | NANOCRYSTAL MICROPARTICLES OF POORLY SOLUBLE DRUGS AND METHODS OF PRODUCTION AND USE THEREOF | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA | 2023-05-04 | — | — | US | disclosed |
| US-20230139842-A1 | NANOCRYSTAL MICROPARTICLES OF POORLY SOLUBLE DRUGS AND METHODS OF PRODUCTION AND USE THEREOF | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230346743-A1 | COMBINATION CANCER THERAPIES | CCNT2, CDK4, CCNT1 | RARB 2855/4885RARG 3284/4885RARA 3148/4885 |
| US-20230139842-A1 | NANOCRYSTAL MICROPARTICLES OF POORLY SOLUBLE DRUGS AND METHODS OF PRODUCTION AND USE THEREOF | ABCB1, EXOSC5, CHMP4B | RARB 2997/4885RARG 2643/4885RARA 2540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.