Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 16/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9152685 | 0.91 | GCGR (0.45) | GCGRTRPM8SLC10A2ALDH1A1L3MBTL1 | |
| SCHEMBL9269784 | 0.90 | GCGR (0.41) | GCGRTRPM8SLC10A2ALDH1A1L3MBTL1 | |
| SCHEMBL9743385 | 0.90 | TRPM8 (0.38) | GCGRTRPM8SLC10A2ALDH1A1L3MBTL1 | |
| SCHEMBL2648227 | 0.82 | GCGR (0.60) | GCGRSLC10A2ALDH1A1L3MBTL1 | |
| SCHEMBL2648212 | 0.82 | GCGR (0.62) | GCGRTRPM8SLC10A2ALDH1A1L3MBTL1 | |
| SCHEMBL2648610 | 0.82 | GCGR (0.53) | GCGRSLC10A2ALDH1A1L3MBTL1 | |
| SCHEMBL2648395 | 0.81 | GCGR (0.52) | GCGRSLC10A2ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL2648307 | 0.80 | GCGR (0.57) | GCGR | |
| SCHEMBL27350569 | 0.80 | GCGR (0.45) | GCGR | |
| SCHEMBL27311063 | 0.78 | GCGR (0.42) | GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218431-B1 | GLUCAGON RECEPTOR ANTAGONISTS FOR THERAPY OF DIABETES AND CONDITIONS ASSOCIATED WITH DIABETES | BAYER CORPORATION | 2001-04-17 | — | — | US | disclosed |
| US-5183897-A | Certain intermediate imino-substituted pyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1993-02-02 | — | — | US | disclosed |