Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.45 |
| ▸ | GRM8 | O00222 | 1/20 | 0.44 |
| ▸ | GRM6 | O15303 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30155394 | 0.79 | ALDH1A1 (0.58) | ALDH1A1HIF1AVCAM1GRM8GRM6 | |
| SCHEMBL2698568 | 0.79 | ALDH1A1 (0.58) | ALDH1A1HIF1AVCAM1GRM8GRM6 | |
| SCHEMBL257444 | 0.78 | VCAM1 (0.51) | ALDH1A1HIF1AVCAM1GRM8GRM6 | |
| SCHEMBL12868652 | 0.77 | ALDH1A1 (0.56) | ALDH1A1HIF1AVCAM1GRM8GRM6 | |
| SCHEMBL28115557 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HIF1AVCAM1GRM8GRM6 | |
| SCHEMBL27734066 | 0.74 | ALDH1A1 (0.53) | ALDH1A1HIF1AVCAM1GRM8GRM6 | |
| SCHEMBL2340870 | 0.74 | EPAS1 (0.56) | ALDH1A1HIF1AVCAM1GRM8GRM6 | |
| SCHEMBL16950918 | 0.74 | ALDH1A1 (0.53) | ALDH1A1HIF1AVCAM1GRM8GRM6 | |
| SCHEMBL16654006 | 0.74 | ALDH1A1 (0.53) | ALDH1A1HIF1AVCAM1GRM8GRM6 | |
| SCHEMBL30783382 | 0.74 | ALDH1A1 (0.45) | ALDH1A1HIF1AVCAM1GRM8GRM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934281-A1 | 1-PHENYL-BENZIMIDAZOLE COMPOUNDS AND THEIR USE AS BAGA- A? RECEPTOR MODULATORS | NEUROSEARCH A/S (DK) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017651-A1 | 1-PHENYL-BENZIMIDAZOLE COMPOUNDS AND THEIR USE AS BAGA-A RECEPTOR MODULATORS | NEUROSEARCH A/S (DK) | 1998-04-30 | — | — | WO | disclosed |