SCHEMBL26477155

SCHEMBL26477155

COC(=O)C(C)CCC(=O)OCc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
MAPK1 P28482 1/20 0.51
KMT2A Q03164 3/20 0.48
MEN1 O00255 2/20 0.48
HPGD P15428 1/20 0.48
LMNA P02545 1/20 0.47
SLC15A1 P46059 1/20 0.45
THRB P10828 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
HSD17B10 Q99714 1/20 0.45
MAPT P10636 2/20 0.44
NOTUM Q6P988 1/20 0.44
POLB P06746 1/20 0.44
ESRRB O95718 1/20 0.44
ATM Q13315 1/20 0.44
TDP1 Q9NUW8 2/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A3 Q01959 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17949819 0.91 ALDH1A1 (0.54) ALDH1A1L3MBTL1MAPK1KMT2AMEN1
SCHEMBL26447162 0.88 ALDH1A1 (0.50) ALDH1A1L3MBTL1MAPK1KMT2ALMNA
SCHEMBL8224834 0.88 ALDH1A1 (0.54) ALDH1A1L3MBTL1MAPK1KMT2AMEN1
SCHEMBL12564571 0.88 ALDH1A1 (0.54) ALDH1A1L3MBTL1MAPK1KMT2AMEN1
SCHEMBL18709165 0.88 ALDH1A1 (0.54) ALDH1A1L3MBTL1MAPK1KMT2AMEN1
SCHEMBL24591323 0.87 ALDH1A1 (0.50) ALDH1A1L3MBTL1MAPK1KMT2AMEN1
SCHEMBL27489823 0.87 ALDH1A1 (0.50) ALDH1A1L3MBTL1MAPK1KMT2AMEN1
SCHEMBL10092579 0.86 ALDH1A1 (0.54) ALDH1A1L3MBTL1MAPK1KMT2AMEN1
SCHEMBL22585411 0.85 LMNA (0.49) ALDH1A1L3MBTL1MAPK1KMT2AMEN1
SCHEMBL30280767 0.85 ALDH1A1 (0.51) ALDH1A1L3MBTL1MAPK1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3389643-B1 NOVEL MURAMYL PEPTIDE DERIVATIVE COMPOUND, SYNTHESIS AND USES THEREOF BHARAT BIOTECH INT LTD (IN) 2023-05-03 EP disclosed