Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17949819 | 0.91 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPK1L3MBTL1TDP1 | |
| SCHEMBL26477155 | 0.88 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPK1L3MBTL1TDP1 | |
| SCHEMBL27489822 | 0.87 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPK1L3MBTL1TDP1 | |
| SCHEMBL11412502 | 0.86 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNAL3MBTL1TDP1 | |
| SCHEMBL25448705 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL27280701 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL21430281 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL27981610 | 0.84 | ABCB1 (0.53) | ALDH1A1KDM4ELMNAMAPK1L3MBTL1 | |
| SCHEMBL11411457 | 0.84 | CTSB (0.51) | ALDH1A1KMT2A | |
| SCHEMBL24591323 | 0.84 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPK1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230138393-A1 | LINKING AMINO ACID SEQUENCES, MANUFACTURING METHOD THEREOF, AND USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230138393-A1 | LINKING AMINO ACID SEQUENCES, MANUFACTURING METHOD THEREOF, AND USE THEREOF | BCAT2, BCAT1, AARS1 | ALDH1A1 3622/4885KDM4E 2001/4885LMNA 779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.