Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | RARB | P10826 | 6/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26480366 | 0.90 | RAB9A (0.52) | RAB9ASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL22275552 | 0.83 | RAB9A (0.60) | RAB9ASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL11016694 | 0.82 | RAB9A (0.58) | RAB9ASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL11016974 | 0.81 | ALDH1A1 (0.61) | RAB9ASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL11018925 | 0.81 | RAB9A (0.57) | RAB9ASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL11017647 | 0.81 | ALDH1A1 (0.61) | RAB9ASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL11014658 | 0.81 | RAB9A (0.57) | RAB9ASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL11018932 | 0.81 | ALDH1A1 (0.61) | RAB9ASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL11016594 | 0.81 | ALDH1A1 (0.61) | RAB9ASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL11015017 | 0.81 | ALDH1A1 (0.61) | RAB9ASMN1; SMN2MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230133817-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2023-05-04 | — | — | US | disclosed |
| US-20230133817-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230133817-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | MRPL21, PEPD, CTSC | RAB9A 2372/4885SMN1; SMN2 1689/4885MAPT 4006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.