Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2663924 | 0.92 | MRGPRX4 (0.46) | MAPTPOLBPTPN1PPARGPTPN2 | |
| SCHEMBL2663789 | 0.88 | PTPN1 (0.45) | MAPTPOLBPTPN1PPARGPTPN2 | |
| SCHEMBL7235286 | 0.84 | TACR1 (0.42) | MAPTPOLBPTPN1PPARGPTPN2 | |
| SCHEMBL23673331 | 0.83 | ALDH1A1 (0.53) | MAPTPOLBPTPN1PPARGPTPN2 | |
| SCHEMBL2650190 | 0.82 | SMN1; SMN2 (0.43) | MAPTMRGPRX4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3269301 | 0.80 | MAPT (0.59) | MAPTMRGPRX4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2664435 | 0.78 | GCGR (0.54) | MAPTPOLBPTPN1PPARGPTPN2 | |
| SCHEMBL3269606 | 0.78 | SMN1; SMN2 (0.47) | MAPTPOLBPPARGNPC1RAB9A | |
| SCHEMBL18002701 | 0.77 | POLB (0.49) | MAPTPOLBPTPN1PPARGPTPN2 | |
| SCHEMBL3271842 | 0.77 | MAOB (0.52) | MAPTMRGPRX4NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-0994848-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |