Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 3/20 | 0.54 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2663789 | 0.84 | PTPN1 (0.45) | RXRARXRBRXRGMAPTRAB9A | |
| SCHEMBL2649711 | 0.84 | GCGR (0.56) | GCGRRXRARXRBRXRGMAPT | |
| SCHEMBL3269606 | 0.82 | SMN1; SMN2 (0.47) | MAPTRAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3269301 | 0.82 | MAPT (0.59) | MAPTRAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2651089 | 0.81 | GCGR (0.47) | GCGRMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13581057 | 0.80 | TUBB1 (0.51) | MAPTSLC6A4ARPOLBMRGPRX4 | |
| SCHEMBL2649925 | 0.80 | RAB9A (0.70) | GCGRRXRARXRBRXRGMAPT | |
| SCHEMBL2664414 | 0.80 | KMT2A (0.49) | GCGRMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2539621 | 0.79 | KDM4E (0.49) | GCGRRXRARXRBRXRGMAPT | |
| SCHEMBL1587491 | 0.79 | CCNB2 (0.47) | RXRARXRBRXRGMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |