Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.35 |
| ▸ | RXRA | P19793 | 4/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8352772 | 0.90 | LOXL2 (0.46) | LOXLOXL2KDM4EMEN1KMT2A | |
| SCHEMBL16065098 | 0.83 | MAPK1 (0.38) | KDM4EMEN1KMT2ANOS3NOS1 | |
| SCHEMBL16065068 | 0.80 | KDM4E (0.35) | LOXLOXL2KDM4EMAPK1CDK5 | |
| SCHEMBL12017658 | 0.79 | UHRF1 (0.43) | LOXLOXL2KDM4EMEN1KMT2A | |
| SCHEMBL17707978 | 0.79 | UHRF1 (0.43) | LOXLOXL2KDM4EMEN1KMT2A | |
| SCHEMBL16065266 | 0.77 | SMN1; SMN2 (0.38) | LOXLOXL2KDM4EMEN1KMT2A | |
| SCHEMBL16065100 | 0.77 | DUT (0.39) | LOXLOXL2KDM4EMEN1KMT2A | |
| SCHEMBL129040 | 0.77 | CRHR1 (0.46) | LOXLOXL2KDM4EMEN1KMT2A | |
| SCHEMBL10187322 | 0.75 | CRHR1 (0.44) | LOXLOXL2KDM4EMEN1KMT2A | |
| SCHEMBL12017657 | 0.75 | KMT2A (0.44) | LOXLOXL2KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023191953-A1 | PNICTOGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND THEIR USE | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES (US) | 2023-10-05 | — | — | WO | disclosed |