Sugi Predict

Sugi Predict / Compounds / SCHEMBL264840

SCHEMBL264840

SCHEMBL264840

CCCCCC(N)C(N)(CCCCC)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ODC1 P11926 1/20 0.44
▸ ARG1 P05089 2/20 0.44
▸ ARG2 P78540 1/20 0.44
▸ MAPT P10636 2/20 0.43
▸ BLM P54132 2/20 0.43
▸ KDM4E B2RXH2 1/20 0.43
▸ LMNA P02545 1/20 0.43
▸ RAB9A P51151 1/20 0.43
▸ PMP22 Q01453 1/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ GRIK1 P39086 2/20 0.42
▸ GRIK2 Q13002 2/20 0.42
▸ SLC1A2 P43004 1/20 0.42
▸ SLC1A1 P43005 1/20 0.42
▸ GPR84 Q9NQS5 4/20 0.40
▸ FFAR1 O14842 1/20 0.40
▸ FDPS P14324 2/20 0.39
▸ TP53 P04637 1/20 0.39
▸ LAP3 P28838 1/20 0.39
▸ LCK P06239 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27507781 0.98 MAPT (0.46) ODC1ARG1ARG2MAPTBLM
SCHEMBL19953119 0.93 MAPT (0.43) ODC1MAPTBLMKDM4ELMNA
SCHEMBL4771385 0.82 ARG1 (0.44) ODC1ARG1ARG2MAPTBLM
SCHEMBL2147212 0.80 ARG1 (0.49) ODC1ARG1ARG2MAPTBLM
SCHEMBL28664660 0.79 HSPD1 (0.54) ARG1ARG2MAPTBLMGRIK1
SCHEMBL28009580 0.78 ARG1 (0.64) ODC1ARG1ARG2MAPTBLM
Water SCHEMBL27925668 0.78 ARG1 (0.64) ODC1ARG1ARG2MAPTBLM
SCHEMBL27734622 0.78 GRIK1 (0.47) MAPTBLMGRIK1GRIK2SLC1A2
SCHEMBL27512214 0.78 GRIK1 (0.47) MAPTBLMGRIK1GRIK2SLC1A2
SCHEMBL11417805 0.78 DPP7 (0.40) ODC1ARG1ARG2MAPTBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2263087-B1 LABELED REACTANTS AND THEIR USES PACIFIC BIOSCIENCES CALIFORNIA INC (US) 2017-08-09 — — EP disclosed
US-9587275-B2 Single molecule sequencing with two distinct chemistry steps PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2017-03-07 — — US disclosed
US-9464107-B2 Labeled nucleotide analogs PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2016-10-11 — — US disclosed
US-9447464-B2 Single molecule sequencing with two distinct chemistry steps PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2016-09-20 — — US disclosed
US-20160010150-A1 SINGLE MOLECULE SEQUENCING WITH TWO DISTINCT CHEMISTRY STEPS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2016-01-14 — — US disclosed
US-8906614-B2 Labeled reactants and their uses PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2014-12-09 — — US disclosed
US-20140186825-A1 LABELED NUCLEOTIDE ANALOGS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2014-07-03 — — US disclosed
US-20140127680-A1 SINGLE MOLECULE SEQUENCING WITH TWO DISTINCT CHEMISTRY STEPS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2014-05-08 — — US disclosed
US-8603741-B2 Single molecule sequencing with two distinct chemistry steps PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2013-12-10 — — US disclosed
US-20130183663-A1 LABELED REACTANTS AND THEIR USES PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2013-07-18 — — US disclosed
US-8133702-B2 Engineered fluorescent dye labeled nucleotide analogs for DNA sequencing PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2012-03-13 — — US disclosed
US-20120028248-A1 ENGINEERED FLUORESCENT DYE LABELED NUCLEOTIDE ANALOGS FOR DNA SEQUENCING PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2012-02-02 — — US disclosed
US-20110311964-A1 LABELED REACTANTS AND THEIR USES PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2011-12-22 — — US disclosed
US-20110212437-A1 SINGLE MOLECULE SEQUENCING WITH TWO DISTINCT CHEMISTRY STEPS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2011-09-01 — — US disclosed
US-7973146-B2 Engineered fluorescent dye labeled nucleotide analogs for DNA sequencing PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2011-07-05 — — US disclosed
US-7968702-B2 Labeled reactants and their uses PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2011-06-28 — — US disclosed
EP-2263087-A1 LABELED REACTANTS AND THEIR USES Pacific Biosciences of California, Inc. (US) 2010-12-22 — — EP disclosed
US-20090246791-A1 ENGINEERED FLUORESCENT DYE LABELED NUCLEOTIDE ANALOGS FOR DNA SEQUENCING PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2009-10-01 — — US disclosed
US-20090233302-A1 LABELED REACTANTS AND THEIR USES PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2009-09-17 — — US disclosed
WO-2009114182-A1 LABELED REACTANTS AND THEIR USES PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2009-09-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110212437-A1 SINGLE MOLECULE SEQUENCING WITH TWO DISTINCT CHEMISTRY STEPS RNGTT, POLL, NUDT21 ODC1 1540/4885ARG1 4880/4885ARG2 4866/4885
US-20090246791-A1 ENGINEERED FLUORESCENT DYE LABELED NUCLEOTIDE ANALOGS FOR DNA SEQUENCING POLM, POLN, POLB ODC1 1597/4885ARG1 4802/4885ARG2 4664/4885
US-20120028248-A1 ENGINEERED FLUORESCENT DYE LABELED NUCLEOTIDE ANALOGS FOR DNA SEQUENCING POLN, POLM, RNGTT ODC1 828/4885ARG1 4734/4885ARG2 4580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.