Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 8/20 | 0.76 |
| ▸ | GSR | P00390 | 1/20 | 0.60 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.58 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23611202 | 0.95 | CPB2 (0.69) | CPB2GSRRNPEPFOLH1SLC6A3 | |
| SCHEMBL28797479 | 0.91 | CPB2 (0.70) | CPB2GSRRNPEPFOLH1SLC6A3 | |
| Hydrochloric Acid SCHEMBL12491698 | 0.91 | CPB2 (0.64) | CPB2GSRRNPEPFOLH1GRIK1 | |
| SCHEMBL1370161 | 0.90 | CPB2 (0.74) | CPB2GSRRNPEPFOLH1SLC6A3 | |
| SCHEMBL7901906 | 0.89 | CPB2 (0.63) | CPB2SLC6A3MEN1ALDH1A1KMT2A | |
| SCHEMBL265335 | 0.89 | CPB2 (0.63) | CPB2SLC6A3MEN1ALDH1A1KMT2A | |
| SCHEMBL15209173 | 0.89 | CPB2 (0.63) | CPB2SLC6A3MEN1ALDH1A1KMT2A | |
| SCHEMBL6892734 | 0.89 | CPB2 (0.63) | CPB2GSRRNPEPFOLH1SLC6A3 | |
| SCHEMBL7901772 | 0.89 | CPB2 (0.63) | CPB2SLC6A3MEN1ALDH1A1KMT2A | |
| SCHEMBL15208444 | 0.89 | CPB2 (0.63) | CPB2SLC6A3MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2263087-B1 | LABELED REACTANTS AND THEIR USES | PACIFIC BIOSCIENCES CALIFORNIA INC (US) | 2017-08-09 | — | — | EP | disclosed |
| US-9464107-B2 | Labeled nucleotide analogs | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-10-11 | — | — | US | disclosed |
| US-8906614-B2 | Labeled reactants and their uses | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2014-12-09 | — | — | US | disclosed |
| US-20140186825-A1 | LABELED NUCLEOTIDE ANALOGS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2014-07-03 | — | — | US | disclosed |
| US-20130183663-A1 | LABELED REACTANTS AND THEIR USES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2013-07-18 | — | — | US | disclosed |
| US-8354252-B2 | Labeled reactants and their uses | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2013-01-15 | — | — | US | disclosed |
| US-8133702-B2 | Engineered fluorescent dye labeled nucleotide analogs for DNA sequencing | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-13 | — | — | US | disclosed |
| US-20120028248-A1 | ENGINEERED FLUORESCENT DYE LABELED NUCLEOTIDE ANALOGS FOR DNA SEQUENCING | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-02-02 | — | — | US | disclosed |
| US-20110311964-A1 | LABELED REACTANTS AND THEIR USES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2011-12-22 | — | — | US | disclosed |
| US-7973146-B2 | Engineered fluorescent dye labeled nucleotide analogs for DNA sequencing | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2011-07-05 | — | — | US | disclosed |
| US-7968702-B2 | Labeled reactants and their uses | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2011-06-28 | — | — | US | disclosed |
| EP-2263087-A1 | LABELED REACTANTS AND THEIR USES | Pacific Biosciences of California, Inc. (US) | 2010-12-22 | — | — | EP | disclosed |
| US-20090246791-A1 | ENGINEERED FLUORESCENT DYE LABELED NUCLEOTIDE ANALOGS FOR DNA SEQUENCING | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2009-10-01 | — | — | US | disclosed |
| US-20090233302-A1 | LABELED REACTANTS AND THEIR USES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2009-09-17 | — | — | US | disclosed |
| WO-2009114182-A1 | LABELED REACTANTS AND THEIR USES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2009-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090246791-A1 | ENGINEERED FLUORESCENT DYE LABELED NUCLEOTIDE ANALOGS FOR DNA SEQUENCING | POLM, POLN, POLB | CPB2 977/4885GSR 2558/4885RNPEP 173/4885 |
| US-20120028248-A1 | ENGINEERED FLUORESCENT DYE LABELED NUCLEOTIDE ANALOGS FOR DNA SEQUENCING | POLN, POLM, RNGTT | CPB2 1564/4885GSR 2771/4885RNPEP 208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.