SCHEMBL1370161

SCHEMBL1370161

NCCCC(CCCN)C(=O)O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 6/20 0.74
GSR P00390 1/20 0.52
RNPEP Q9H4A4 1/20 0.50
HDAC1 Q13547 2/20 0.48
HDAC2 Q92769 2/20 0.48
CHRM1 P11229 1/20 0.48
AKR1A1 P14550 1/20 0.48
CHRM3 P20309 1/20 0.48
HTR2A P28223 1/20 0.48
HTR2C P28335 1/20 0.48
ADRA1A P35348 1/20 0.48
HRH1 P35367 1/20 0.48
DRD3 P35462 1/20 0.48
SLC6A3 Q01959 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
FOLH1 Q04609 3/20 0.46
CA2 P00918 1/20 0.46
MAPK1 P28482 1/20 0.46
GABRR1 P24046 3/20 0.44
GABRR3 A8MPY1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8536227 0.97 CPB2 (0.71) CPB2GSRRNPEPHDAC1HDAC2
SCHEMBL14453643 0.95 CPB2 (0.68) CPB2GSRRNPEPHDAC1HDAC2
SCHEMBL9817605 0.90 CPB2 (0.68) CPB2GSRRNPEPHDAC1HDAC2
SCHEMBL23611202 0.90 CPB2 (0.69) CPB2GSRRNPEPHDAC1HDAC2
SCHEMBL264890 0.90 CPB2 (0.76) CPB2GSRRNPEPHDAC1HDAC2
SCHEMBL27816843 0.89 CPB2 (0.61) CPB2GSRRNPEPHDAC1HDAC2
SCHEMBL9747951 0.89 CHRM1 (0.70) CPB2GSRRNPEPHDAC1HDAC2
SCHEMBL27581250 0.87 CPB2 (0.65) CPB2GSRRNPEPCA2MAPK1
Hydrochloric Acid SCHEMBL8420827 0.87 CHRM1 (0.67) CPB2GSRRNPEPHDAC1HDAC2
Hydrochloric Acid SCHEMBL12491698 0.85 CPB2 (0.64) CPB2GSRRNPEPFOLH1GABRR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12527880-B2 Cyanine-based telodendrimers and uses for treating cancer THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-01-20 US claimed
US-20250000811-A1 TELODENDRIMER NANOCARRIERS FOR MONOMERIC AMPHOTERICIN B DELIVERY UNIV NEW YORK STATE RES FOUND (US) 2025-01-02 US claimed
CN-118649242-A Application of amphiphilic dendritic polypeptide in oral delivery of peptide drugs 上海胜普泽泰医药科技有限公司 2024-09-17 CN claimed
CN-118620025-A Amphiphilic dendritic polypeptide molecule, synthesis method thereof and self-assembly method 厦门大学 2024-09-10 CN claimed
US-11649326-B2 Functional, segregated, charged telodendrimers and nanocarriers and methods of making and using same THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2023-05-16 US claimed
US-20230076792-A1 SEQUENTIAL TARGETING IN CROSSLINKING NANO-THERANOSTICS FOR TREATING BRAIN TUMORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-03-09 US claimed
CN-115551917-A Sequential targeting of cross-linked nanotherapeutics for the treatment of brain tumors 加利福尼亚大学董事会 2022-12-30 CN claimed
EP-4077477-A1 SEQUENTIAL TARGETING IN CROSSLINKING NANO-THERANOSTICS FOR TREATING BRAIN TUMORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-10-26 EP claimed
US-11406714-B2 Telodendrimers and nanocarriers and methods of using same THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2022-08-09 US claimed
EP-3347053-B1 FUNCTIONAL, SEGREGATED, CHARGED TELODENDRIMERS AND NANOCARRIERS AND METHODS OF MAKING AND USING SAME THE RESEARCH FOUNDATION FOR STATE UNIV OF NEW YORK (US) 2022-05-25 EP claimed
US-20140161719-A1 PORPHYRIN MODIFIED TELODENDRIMERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-06-12 US claimed
CN-103748142-A Reversibly crosslinked micelle systems UNIV CALIFORNIA 2014-04-23 CN claimed
EP-2707419-A2 REVERSIBLY CROSSLINKED MICELLE SYSTEMS The Regents of the University of California (US) 2014-03-19 EP claimed
WO-2013096388-A1 TELODENDRIMERS WITH ENHANCED DRUG DELIVERY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-06-27 WO claimed
CN-102159189-B Nanocarriers for drug delivery UNIV CALIFORNIA 2013-06-12 CN claimed
WO-2012158622-A2 REVERSIBLY CROSSLINKED MICELLE SYSTEMS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-11-22 WO claimed
US-20110286915-A1 Nanocarriers for Drug Delivery THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-11-24 US claimed
CN-102159189-A Nanocarriers for drug delivery UNIV CALIFORNIA 2011-08-17 CN claimed
EP-2344134-A2 NANOCARRIERS FOR DRUG DELIVERY The Regents of the University of California (US) 2011-07-20 EP claimed
WO-2010039496-A2 NANOCARRIERS FOR DRUG DELIVERY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-04-08 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140161719-A1 PORPHYRIN MODIFIED TELODENDRIMERS CETP, NR1H4, ABCB4 CPB2 685/4885GSR 225/4885RNPEP 2046/4885
US-20110286915-A1 Nanocarriers for Drug Delivery CLTA, EPCAM, EGFR CPB2 3615/4885GSR 1966/4885RNPEP 3519/4885
US-12527880-B2 Cyanine-based telodendrimers and uses for treating cancer TUBB1, CA13, YWHAZ CPB2 1490/4885GSR 2934/4885RNPEP 1971/4885
US-20230076792-A1 SEQUENTIAL TARGETING IN CROSSLINKING NANO-THERANOSTICS FOR TREATING BRAIN TUMORS TIE1, CA12, CA13 CPB2 2940/4885GSR 1099/4885RNPEP 3233/4885
US-11406714-B2 Telodendrimers and nanocarriers and methods of using same TTI2, MTCL3, HTT CPB2 3709/4885GSR 223/4885RNPEP 2278/4885
US-11649326-B2 Functional, segregated, charged telodendrimers and nanocarriers and methods of making and using same TSPO, TBCA, TTI2 CPB2 2883/4885GSR 1515/4885RNPEP 1729/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.