Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28636994 | 0.91 | DNM1 (0.47) | DNM1MAPTGBA1THRBTSHR | |
| SCHEMBL7213119 | 0.88 | DNM1 (0.43) | DNM1MAPTGBA1LPAR1LPAR3 | |
| SCHEMBL5031261 | 0.86 | DNM1 (0.42) | DNM1MAPTTHRBTSHRMEN1 | |
| SCHEMBL10819065 | 0.86 | DNM1 (0.42) | DNM1MAPTTHRBTSHRMEN1 | |
| SCHEMBL31296249 | 0.83 | ADRB2 (0.38) | DNM1MAPTTSHR | |
| SCHEMBL29143221 | 0.80 | DNM1 (0.54) | DNM1MAPTTHRBTSHRLPAR1 | |
| SCHEMBL2370147 | 0.80 | DNM1 (0.54) | DNM1MAPTTHRBTSHRLPAR1 | |
| SCHEMBL6134150 | 0.80 | USP2 (0.47) | DNM1MAPTTHRBTSHRLPAR1 | |
| SCHEMBL5597717 | 0.78 | DNM1 (0.35) | DNM1MAPTTHRBTSHRLPAR1 | |
| SCHEMBL2369842 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934274-A1 | SUBSTITUTED PYRIDINES AND BIPHENYLS AS ANTI-HYPERCHOLESTERINEMIC, ANTI-HYPERLIPOPROTEINEMIC AND ANTI-HYPERGLYCEMIC AGENTS | Bayer Corporation (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998004528-A2 | SUBSTITUTED PYRIDINES AND BIPHENYLS AS ANTI-HYPERCHOLESTERINEMIC, ANTI-HYPERLIPOPROTEINEMIC AND ANTI-HYPERGLYCEMIC AGENTS | BAYER CORPORATION (US) | 1998-02-05 | — | — | WO | disclosed |