Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 14/20 | 0.50 |
| ▸ | ADCYAP1R1 | P41586 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | COL1A1 | P02452 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28743047 | 0.86 | GCGR (0.51) | GCGRADCYAP1R1IDO1COL1A1RXRA | |
| SCHEMBL17129257 | 0.85 | GCGR (0.50) | GCGRADCYAP1R1IDO1 | |
| SCHEMBL2650257 | 0.81 | ALDH1A1 (0.59) | GCGRADCYAP1R1 | |
| SCHEMBL17129362 | 0.79 | GCGR (0.44) | GCGRADCYAP1R1COL1A1 | |
| SCHEMBL7235710 | 0.78 | GCGR (0.61) | GCGRADCYAP1R1 | |
| SCHEMBL27517422 | 0.78 | ACHE (0.50) | GCGRADCYAP1R1IDO1 | |
| SCHEMBL7235715 | 0.77 | GCGR (0.60) | GCGRADCYAP1R1RXRARXRB | |
| SCHEMBL27517753 | 0.75 | COL1A1 (0.44) | GCGRADCYAP1R1IDO1COL1A1RXRA | |
| SCHEMBL22858195 | 0.73 | MAPK1 (0.47) | GCGRIDO1 | |
| SCHEMBL2650562 | 0.71 | ALDH1A1 (0.79) | GCGRADCYAP1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994848-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |