Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | HTR3A | P46098 | 6/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.46 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 5/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2366486 | 0.80 | ADRB1 (0.57) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL2649131 | 0.75 | ADRB1 (0.42) | ALDH1A1SMN1; SMN2HTR3AHTR3EHTR3B | |
| SCHEMBL28621356 | 0.75 | HTR1A (0.51) | HTR3AADRB1HTR7HTR1A | |
| SCHEMBL2649516 | 0.73 | ADRB1 (0.51) | ALDH1A1SMN1; SMN2HTR3AHTR3EHTR3B | |
| SCHEMBL2649642 | 0.72 | HTR1A (0.41) | ALDH1A1SMN1; SMN2HTR3AADRB1HTR7 | |
| SCHEMBL17884970 | 0.72 | ADRB1 (0.53) | ALDH1A1HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL30609659 | 0.72 | ADRB1 (0.52) | ALDH1A1HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL30609616 | 0.72 | ADRB1 (0.53) | ALDH1A1HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL17884851 | 0.72 | ADRB1 (0.52) | ALDH1A1HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL28572112 | 0.71 | LMNA (0.49) | ALDH1A1SMN1; SMN2ADRB1HTR7HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-0994848-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |